Author's response to reviews Title:Genetic analysis of an allergic rhinitis cohort reveals an intercellular epistasis between FAM134B and CD39 Authors:

Author's response to reviews Title: Single nucleotide polymorphisms in thymic stromal lymphopoietin gene are not associated with allergic rhinitis susceptibility in Chinese subjects Authors:

Botulinum Toxin Type A on an Intranasal Sponge for Chronic Allergic Rhinitis: Randomized Clinical Trial

Objectives: In this study, we examined the effect of botulinum toxin A (BTA) on chronic allergic rhinitis (CAR). We tested the effects of BTA, applied to an intranasal sponge, on patients who had CAR for a minimum of three years and had been treated unsuccessfully with conventional medications. Methods:The study was an interventional case-control single-blind randomized clinical trial. Forty...

Serum Level of Selenium, IL-4, IL-10 & IFN-g in Patients with Allergic Asthma, Allergic Rhinitis and Healthy Controls

Background: Allergic diseases have increased during the past decade worldwide. Th2 type lymphocyte response is known to play an important role in the process of allergic inflammation. IL-4, a mediator of type II cytokine response increases IgE synthesis and Interferon gamma, a cytokine of type I response interferes with IL-4 and inhibits IgE production. Selenium is an essential component of glu...

Author's response to reviews Title: Clinical profile, outcome and improvement in quality of life in patients with allergic rhinitis Authors:

بررسی تأثیر ژنوتیپ‌های پلی‌مورفیسم -137G/C از ژن اینترلوکین 18 بر روی سطح ایمونوگلوبین E سرمی در بیماران مبتلا به رینیت آلرژیک

Background: Allergic rhinitis, a chronic inflammatory disease of the upper airways, has a major effect on the life quality of patients. The inflammatory response in the nasal mucosa includes an immediate IgE-mediated response by mast cell, so that the late phase of response is characterized by recruitment of eosinophilsand  basophils. IL-18 is a member of the IL-1 family and originally is ...